Arnold S. Freedman, MD

Dana-Farber Cancer Institute

Academic Titles

Professor, Medicine, Harvard Medical School

Research Program Affiliation

Member, Cancer Immunology

Member, Lymphoma and Myeloma

Research Abstract

My laboratory focus is on how the malignant microenvironment affects the growth and survival of B cell leukemias and lymphomas. This involves studies of supportive cells and the cell-cell contact and soluble factors which they provide for malignant B cells. In the area of clinical research, I have focused on the role of high dose therapy in indolent lymphomas and strategies to improve this treatment. This includes improvements in purging tumor cells from the normal hematopoietic stem cells and post-transplant therapies using immunotherapeutic approaches with cytokines and monoclonal antibodies.