Elizabeth A. Mittendorf, MD, PhD

Brigham And Women's Hospital

Academic Titles

Karen and Rob Hale Distinguished Chair in Surgical Oncology, Surgery, Harvard Medical School

Research Program Affiliation

Member, Cancer Immunology

Co-Leader, Breast Cancer

Research Abstract

Dr. Mittendorf focuses her clinical and laboratory efforts on the study of breast cancer with a specific interest in immunotherapy. She has been the PI on a number of clinical protocols informed by work from her laboratory including a multicenter trial investigating a CD8+ T cell eliciting vaccine in combination with trastuzumab and a multicenter trial supported by SU2C evaluating the combination of ipatasertib and atezolizumab in triple negative breast cancer. The current focus of her laboratory work is to determine the impact of standard and experimental therapies on immunologic aspects of the tumor microenvironment to inform rational trials of immunotherapeutic agents.