Stefan A. Carp, PhD

Massachusetts General Hospital

Academic Titles

Associate Professor, Radiology, Harvard Medical School

Research Program Affiliation

Member, Breast Cancer

Research Abstract

My research focuses on the development of novel optical instrumentation for non-invasive tissue monitoring and the translation of these techqniques for clinical use. In particular, I am interested in the application of near-infrared diffuse optical tomography techniques for breast cancer diagnosis and chemotherapy guidance. We have recently shown that dynamic changes in tissue blood volume during fractional mammographic-like compression can be used to assess the early response of malignant lesions to neoadjuvant chemotherapy. I am currently preparing to conduct a follow-up study, that uses a multi-modal optical imaging system combined with digital breast tomosynthesis to characterize the outcome early prediction performance of dynamic optical biomarkers assessed during a multi-stage breast compression maneuver for HER2+ and TNBC patients undergoing NACT.