Neoadjuvant Chemotherapy With or Without Radiotherapy in Resected Pancreatic Ductal Adenocarcinoma.
De Stefano F, Wu NF, Belfiori G, Roberts HJ, Ferrone C, Aleotti F, Allen JN, Balzano G, Blaszkowsky LS, Clark JW, De Cobelli F, Fagenholz PJ, Gasparini G, Harrison JM, Hong TS, Lester NA, Palumbo D, Pathak PS, Pecorelli N, Lena MS, Tang R, Tamburrino D, Weekes CD, Qadan M, Partelli S, Lillemoe KD, Ryan DP, Wo JY, Crippa S, Falconi M, Fernández-Del Castillo C
Differential T cell clonal dynamics underlie outcomes to frontline chemoimmunotherapy in advanced gastric cancer.
Wright SJ, Kang S, An M, Heo YJ, Parikh M, Bi L, Lee H, Moorhead G, Haradhvala N, Lim SH, Kim ST, Getz G, Hacohen N, Lee J, Mehta A, Klempner SJ, Park RJ
Driving tumor-associated macrophages to a CXCL9/SPP1 phenotype eliminates pancreatic cancer.
Nguyen YTM, Pfefferlé M, Oh J, Simpson GG, Walker SA, Noguchi S, Garris CS, Deutsch-Williams RJ, Wirapati P, De Stefano F, Goemans M, Dai R, Vinegoni C, Fernández Del Castillo C, Liss AS, Pittet MJ, Weissleder R
Addition of High-Dose Vitamin D3 to Standard Treatment in Patients With Metastatic Colorectal Cancer: The SOLARIS Randomized Clinical Trial (Alliance A021703).
Ng K, Ou FS, Zemla T, Jackson NA, Kalyan A, Devoe C, Shusterman M, Vijayvergia N, Wu CS, Cohen SA, Pulsipher S, Shergill A, Watson Y, Kleiber B, Lee M, Kohn CG, Thalappillil JS, Schwartz LH, Zuckerman D, Hollis BW, O'Reilly EM, Meyerhardt JA
Daraxonrasib in Previously Treated Advanced -Mutated Pancreatic Cancer.
Wolpin BM, Park W, Garrido-Laguna I, Spira A, Starodub A, Sommerhalder D, Punekar SR, Barve M, Pelster M, Herzberg B, Azad NS, Hecht JR, Ou SHI, Lin T, Kar S, Tao L, Vora R, Hegde A, Aung K, Hong DS,
Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer.
O'Reilly EM, Wainberg ZA, Hendifar AE, Borad MJ, Pietrantonio F, Pant S, Hammel P, Cremolini C, Manji GA, Oberstein PE, Garrido-Laguna I, Springfeld C, Azad NS, Ueno M, Chui SY, Zhang Y, Patel H, Lee Y, Salman Z, Wolpin BM,
Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial.
Merriam P, Morrow JJ, Mazzola E, Solimini NL, Gokhale PC, Chi P, Chen AP, Agulnik M, Burgess M, Schuetze SM, Somaiah N, Van Tine BA, Pollack SM, Tinoco G, Trent J, Wilky BA, Bothwick N, Eschle BK, Nguyen V, Beumer JH, Rastkari N, Jiwani S, Wu PI, Pelosof L, Hemming ML, Shapiro GI, Demetri G, Bernstein B, George S
Dietary sulfur amino acids enhance anti-tumor immunity in colon cancer via an NKT cell-XCL1-cDC1 circuit.
Lobel L, Fonseca-Pereira D, Nakatsu G, Michaud M, Cao YG, Bae S, Krabak C, Oren Y, Clay SL, El Tekle G, Chun E, Kon S, Chan AT, Clardy J, Glickman JN, Ajami NJ, Day A, Damania A, Baruch EN, White MG, Diggs LP, Wargo J, Riffelmacher T, Balancio A, Kronenberg M, Huttenhower C, Garrett WS
Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny.
Singh PN, Hadj Bachir E, Howe JR, Bellizzi AM, Cejas P, Madha-Krause S, Epstein CB, Chan J, Bernstein BE, Kulke MH, Zhou Q, Shivdasani RA
GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma.
Gong D, Guo JA, Su J, Cetinkaya S, Hennessey C, Yu P, Jambhale A, Wang PL, Caldwell NJ, Lam A, Wang J, Shiau C, Kapner KS, Dilly J, Abbassi L, Chugh S, Dasgupta S, Nowak J, Wolpin BM, Zhang ML, Mino-Kenudson M, Jacks T, Aguirre AJ, Hwang WL
First-line zolbetuximab plus mFOLFOX6 and nivolumab in unresectable CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: a phase 2 trial.
Shitara K, Shoji H, Fazio N, Lonardi S, Lee KW, Bai LY, Yamaguchi K, Metges JP, Masi G, Smith D, Kim TY, Matsangou M, Shrivastava A, Zhou M, Hill J, Guerrero A, Wang X, Zaanan A, Klempner SJ
Hepatic adaptation to chronic metabolic stress primes tumorigenesis.
Tzouanas CN, Shay JES, Sherman MS, Rubin AJ, Mead BE, Dao TT, Tao J, Lehrich BM, Eng G, Patterson-Fortin J, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong YE, Joung J, Chi F, McMahon-Skates T, Winston CL, Jeong WJ, Aney KJ, Chen E, Nissim S, Zhang F, Deshpande V, Monga SP, Lauer GM, Goessling W, Yilmaz ÖH, Shalek AK
